摘要 |
PURPOSE: A manufacturing method of alcohol derivative is provided to reduce a use amount of metal, to obtain high yield at room temperature in short time, and to be suitable for manufacturing alcohol for medicine and perfume by using environmental-friendly isopropanol as a solvent and indium which has less toxicity as solvents. CONSTITUTION: A manufacturing method of alcohol derivative comprises: a step of preparing an alcohol derivative in chemical formula 1 by reacting an aldehyde derivative in chemical formula 2 and an indium alkoxide derivative in chemical formula 3. In chemical formula 1-3, R is (C1-C10)alkyl, (C3-C12) cycloalkyl, (C6-C12) aryl, (C3-C12)heteroaryl, a functional group in chemical formula (a) or a functional group in chemical formula (b), R^11-R^15 is independently hydrogen, halogen, (C1-C10)alkyl or (C3-C12)aryl, and R^1 and R^2 is (C1-C10)alkyl. |