发明名称 |
LIPOPHILIC PHOSPHORAMIDE COMPOUNDS AND USES THEREOF |
摘要 |
The present invention has for an object a cationic lipophilic compound of the following general formula (I): (see formula I) wherein: a) R1 and R'1 each represent, independently from one another, an alkyl chain, an alkenyl chain or a polyalkenyl chain with from 10 to 24 carbon atoms, with the polyalkenyl chain having from 2 to 4 double links; b) R2 is a hydrogen atom or an alkyl chain having from 1 to 4 carbon atoms; and R3 is a group with the following formula (IIa) -(CH2)n-or following formula (IIb) -C(=NH)-NH-(CH2)n-wherein: - n is an integer equal to 0, 1, 2, 3 or 4; and d) A+ is an organic cation; e) X- is an anion.
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申请公布号 |
CA2505414(C) |
申请公布日期 |
2013.03.12 |
申请号 |
CA20032505414 |
申请日期 |
2003.11.07 |
申请人 |
CENTRE NATIONALE DE LA RECHERCHE SCIENTIFIQUE (CNRS);INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM);UNIVERSITE DE BRETAGNE OCCIDENTALE;CENTRE HOSPITALIER UNIVERSITAIRE DE BREST |
发明人 |
DES ABBAYES, HERVE;YAOUANC, JEAN-JACQUES;CLEMENT, JEAN-CLAUDE;LE NY, KARINE;FEREC, CLAUDE;MONTIER, TRISTAN;DELEPINE, PASCAL |
分类号 |
C07F9/24;A61K9/127;A61K9/133;C07F9/54;C07F9/59;C07F9/6506;C07F9/6539;C07F9/72;C12N15/87 |
主分类号 |
C07F9/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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