发明名称 LIPOPHILIC PHOSPHORAMIDE COMPOUNDS AND USES THEREOF
摘要 The present invention has for an object a cationic lipophilic compound of the following general formula (I): (see formula I) wherein: a) R1 and R'1 each represent, independently from one another, an alkyl chain, an alkenyl chain or a polyalkenyl chain with from 10 to 24 carbon atoms, with the polyalkenyl chain having from 2 to 4 double links; b) R2 is a hydrogen atom or an alkyl chain having from 1 to 4 carbon atoms; and R3 is a group with the following formula (IIa) -(CH2)n-or following formula (IIb) -C(=NH)-NH-(CH2)n-wherein: - n is an integer equal to 0, 1, 2, 3 or 4; and d) A+ is an organic cation; e) X- is an anion.
申请公布号 CA2505414(C) 申请公布日期 2013.03.12
申请号 CA20032505414 申请日期 2003.11.07
申请人 CENTRE NATIONALE DE LA RECHERCHE SCIENTIFIQUE (CNRS);INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM);UNIVERSITE DE BRETAGNE OCCIDENTALE;CENTRE HOSPITALIER UNIVERSITAIRE DE BREST 发明人 DES ABBAYES, HERVE;YAOUANC, JEAN-JACQUES;CLEMENT, JEAN-CLAUDE;LE NY, KARINE;FEREC, CLAUDE;MONTIER, TRISTAN;DELEPINE, PASCAL
分类号 C07F9/24;A61K9/127;A61K9/133;C07F9/54;C07F9/59;C07F9/6506;C07F9/6539;C07F9/72;C12N15/87 主分类号 C07F9/24
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