COMBINATION OF A RECOMBINANT MYCOBACTERIUM AND A BIOLOGICALLY ACTIVE AGENT AS A VACCINE

摘要

The present invention is related to a combination comprising a first constituent and a second constituent, wherein the first constituent is a bacterial cell which comprises at least one recombinant nucleic acid molecule encoding a phagolysosomal escape peptide or polypeptide, wherein the bacterial cell is a Mycobacterium cell; and wherein the second constituent is a biologically active agent capable of eliciting an immune response.