发明名称 METHOD OF OBTAINING BRUSHITE-TYPE CEMENT FOR REPLACEMENT OF BONE DEFECTS
摘要 FIELD: medicine.SUBSTANCE: invention relates to field of medicine, namely to dentistry, and deals with obtaining brushite-type cement for replacement of bone defects. Method includes dosed, in equal volume ratios, mixing of two water-based pastes. Composition of first paste includes as mineral filling agent nano-size hydroxyapatite with size of crystals 30-40×100-200 nm in form of 10-20% water suspension; composition of second paste includes sulfate of monovalent metal, namely sodium sulfate or mixture of sodium sulfate and potassium sulfate with ratio 20:1. Composition of first paste, wt %: ?-tricalcium phosphate 50-70%, nano-size hydroxyapatite with size of crystals 30-40×100-200 nm - 2-10%, distilled water - to 100. Composition of second paste, wt %: monocalcium phosphate monohydrate - 47-65%, sulphate of monovalent metal - 5-22%, distilled water - 30-48%. Composition of pastes ensures their sedimentation stability, which makes it possible to sterilise material directly in any dosing device and dose pastes for cement obtaining correctly. Time of complete cement solidification constitutes 4-5 minutes, pH stabilisation takes place within 2 hours.EFFECT: obtained by claimed method brushite-type cement possesses mechanical strength not lower than 15-20 MPa.1 tbl, 7 ex, 1 dwg
申请公布号 RU2477120(C2) 申请公布日期 2013.03.10
申请号 RU20110112933 申请日期 2011.04.04
申请人 FEDERAL'NOE GOSUDARSTVENNOE AVTONOMNOE OBRAZOVATEL'NOE UCHREZHDENIE VYSSHEGO PROFESSIONAL'NOGO OBRAZOVANIJA "BELGORODSKIJ GOSUDARSTVENNYJ NATSIONAL'NYJ ISSLEDOVATEL'SKIJ UNIVERSITET"(NIU "BELGU") 发明人 TRIFONOV BORIS VASIL'EVICH;KUZ'MINA ELENA ALEKSANDROVNA;KOLOBOVA ELENA GRIGOR'EVNA;LAZEBNAJA MARIJA ALEKSEEVNA
分类号 A61K6/00;A61L24/02;A61L27/12 主分类号 A61K6/00
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