| 发明名称 |
ANTI-VEGF ANTIBODIES |
| 摘要 |
Humanized and variant anti-VEGF antibodies and various uses therefor are disclosed. The anti-VEGF antibodies have strong binding affinities for VEGF; inhibit VEGF-induced proliferation of endothelial cells in vitro; and inhibit tumor growth in vivo. |
| 申请公布号 |
US2013058927(A1) |
申请公布日期 |
2013.03.07 |
| 申请号 |
US201213665810 |
申请日期 |
2012.10.31 |
| 申请人 |
GENENTECH, INC.;GENENTECH, INC. |
发明人 |
BACA MANUEL;WELLS JAMES A.;PRESTA LEONARD G.;LOWMAN HENRY B.;CHEN YVONNE MAN-YEE |
| 分类号 |
A61K39/395;A61P9/00;A61P27/02;A61P35/00;C07K16/22;C07K16/46;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/62;C12N15/63;C12P21/02 |
主分类号 |
A61K39/395 |
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