| 发明名称 |
ENCAPSULATED N-ACETYLMANNOSAMINE OR N-ACETYLNEURAMINIC ACID TO INCREASE SIALYLATION |
| 摘要 |
A method for treating a disorder characterized by hyposialylation in a subject that includes administering to the subject an effective amount of (i) a composition comprising N-acetylmannosamine, or a derivative thereof, encapsulated within a liposome, or (ii) a composition comprising N-acetylneuraminic acid, or a derivative thereof, encapsulated within a liposome, wherein the liposome comprises 1,2-dioleoyl-3-trimethylammonium-propane and cholesterol.
|
| 申请公布号 |
US2013058998(A1) |
申请公布日期 |
2013.03.07 |
| 申请号 |
US201213605946 |
申请日期 |
2012.09.06 |
| 申请人 |
HUIZING MARJAN;YARDENI TAL;JAY CHRISTOPHER M.;TEMPLETON NANCY SMYTH;GAHL WILLIAM A.;UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES |
发明人 |
HUIZING MARJAN;YARDENI TAL;JAY CHRISTOPHER M.;TEMPLETON NANCY SMYTH;GAHL WILLIAM A. |
| 分类号 |
A61K31/7028;A61K9/127;A61P13/12;A61P25/28;A61P35/00 |
主分类号 |
A61K31/7028 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
