发明名称 |
TREATING PRIMARY SCLEROSING CHOLANGITIS |
摘要 |
A method for treating primary sclerosing cholangitis comprises applying peripheral blood from a patient or subject to an apheresis column loaded with a solid support comprising one or more binding reagents capable of specifically binding to a chemokine receptor, optionally the chemokine receptor CCR9, CXCR4, CCR7 or CCR5 immobilized directly or indirectly on the support thus removing one or more chemokine receptor, optionally CCR9, CXCR4, CCR7 and CCR5 expressing cells from the peripheral blood of the patient or subject. Various companion therapeutic methods and useful binding reagents are also described. |
申请公布号 |
WO2012172343(A3) |
申请公布日期 |
2013.03.07 |
申请号 |
WO2012GB51353 |
申请日期 |
2012.06.13 |
申请人 |
ITH IMMUNE THERAPY HOLDINGS;COTTON, GRAHAM;WINQVIST, OLA |
发明人 |
COTTON, GRAHAM;WINQVIST, OLA |
分类号 |
C07K14/52;A61M1/36;B01J20/32;C07K17/02;G01N33/68 |
主分类号 |
C07K14/52 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|