摘要 |
The present disclosure provides methods for identifying therapeutic agents that are multifunctional radical quenchers. It also provides compounds of formula (I), (II), or (II-A): and pharmaceutically acceptable salts thereof, compositions comprising these compounds, and methods of using these compounds in a variety of applications, such as treatment or suppression of diseases associated with decreased mitochondrial function resulting in diminished ATP production and/or oxidative stress and/or lipid peroxidation. |
申请人 |
ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THESTATE OF ARIZONA, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY;HECHT, SIDNEY;KHDOUR, OMAR;CHOWDHURY, SANDIPAN, ROY;TALUKDER, POULAMI |
发明人 |
HECHT, SIDNEY;KHDOUR, OMAR;CHOWDHURY, SANDIPAN, ROY;TALUKDER, POULAMI |