发明名称 CELL SURVIVAL PROMOTION METHOD USING NEUROTROPHIN ANALOG
摘要 <P>PROBLEM TO BE SOLVED: To provide a compound for treating a neurodegenerative disease and other diseases. <P>SOLUTION: This compound has binding specificity to p75<SP POS="POST">NTR</SP>receptor molecule, and is expressed by formula (II); where in formula, n is an integer of 0-8; L<SB POS="POST">2</SB>is alkylene or the like; R<SB POS="POST">3</SB>is H, alkyl or the like; A<SB POS="POST">5</SB>is selected from the group consisting of N and CH; B<SB POS="POST">4</SB>and B<SB POS="POST">5</SB>are each selected from the group consisting of O, S and NR<SB POS="POST">4</SB>(in formula, R<SB POS="POST">4</SB>is H, alkyl or the like); and D<SB POS="POST">2</SB>is selected from amino or the like. <P>COPYRIGHT: (C)2013,JPO&INPIT
申请公布号 JP2013047236(A) 申请公布日期 2013.03.07
申请号 JP20120220524 申请日期 2012.10.02
申请人 UNIV OF NORTH CAROLINA AT CHAPEL HILL;US GOVERNMENT REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS OFFICE OF THE GENERAL COUNSEL 发明人 LONGO FRANK M;MASSA STEPHEN M
分类号 C07D295/12;A61K31/155;A61K31/451;A61K31/496;A61K31/522;A61K31/5375;A61K45/00;A61P9/10;A61P17/14;A61P25/00;A61P25/08;A61P25/14;A61P25/16;A61P25/28;C07D295/22;C07D473/08 主分类号 C07D295/12
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