发明名称 |
CRYSTAL OF DI(ARYLAMINO)ARYL COMPOUND |
摘要 |
Provided are crystals of compound A which have properties suitable for industrial production. MEANS FOR SOLVING As the results of intensive studies to provide crystals of compound A having an inhibitory activity on the kinase activity of an EML4-ALK fusion protein and a mutant EGFR protein, crystals of compound A were found. Moreover, it was found that A04-type crystal of compound A, from among the aforesaid crystals of compound A, unexpectedly have preferred properties as a drug substance.
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申请公布号 |
US2013059855(A1) |
申请公布日期 |
2013.03.07 |
申请号 |
US201113698183 |
申请日期 |
2011.05.16 |
申请人 |
SHIMADA ITSURO;HIRAKURA YUTAKA;YAMAZAKI KOUJI;TAKEGUCHI KAZUHIRO;UEDA NORIHIRO;ASTELLAS PHARMA INC. |
发明人 |
SHIMADA ITSURO;HIRAKURA YUTAKA;YAMAZAKI KOUJI;TAKEGUCHI KAZUHIRO;UEDA NORIHIRO |
分类号 |
A61K31/53;A61P35/00;C07D401/14 |
主分类号 |
A61K31/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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