<p>An objective of the present invention is to provide a MUC1 antibody having high specificity to cancer cells. The objective has been achieved by the present inventors who found that a cancer-specific sugar chain can be specifically recognized in MUC1 and a cancer cell expressing MUC1 having such a cancer cell specific sugar chain can be recognized. The present invention provides an antibody, an antigen-binding fragment thereof or a MUC1-binding molecule, having, for example, 40-fold specificity or more for a cancer-associated structure of MUC1 as compared to that of a normal tissue-associated structure of MUC1.</p>
申请公布号
EP2565268(A1)
申请公布日期
2013.03.06
申请号
EP20110774654
申请日期
2011.04.28
申请人
SHIONOGI & CO., LTD.;NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY