发明名称 |
LOW-OIL PHARMACEUTICAL EMULSION COMPOSITIONS COMPRISING PROGESTOGEN |
摘要 |
The invention relates to a sterile, ready-to-use, pharmaceutical oil-in water emulsion composition for parenteral administration comprising: 0.015 to 1.2% wt./vol. of progestogen; 0.5-30% wt./vol.oil, wherein the oil comprises at least 85% wt.wt. triglyceride; 0.0425-12.5% wt./vol phospholipid; 61.4-99.4% wt./vol. aqueous medium; wherein the phospholipid is present in an amount of 6.8% - 43% of the oil (wt./wt.), and wherein the progestogen is present in an amount greater than or equal to 2.1wt% of the oil, preferably greater than or equal to 2.2wt% of the oil. The invention further relates to the use of the aforementioned composition in therapeutic or prophylactic treatment, said treatment comprising intravenous administration of the pharmaceutical composition. |
申请公布号 |
EP2563335(A2) |
申请公布日期 |
2013.03.06 |
申请号 |
EP20110717561 |
申请日期 |
2011.04.26 |
申请人 |
BESINS HEALTHCARE LUXEMBOURG SARL |
发明人 |
PICKERSGILL, LAURA;DI HOISER, EVA-MARIA;ACHLEITNER, GEORG |
分类号 |
A61K9/107;A61K9/00;A61K31/57;A61K47/06;A61K47/10;A61K47/12 |
主分类号 |
A61K9/107 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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