| 发明名称 |
MODULATION OF TRANSTHYRETIN EXPRESSION |
| 摘要 |
Provided herein are methods, compounds, and compositions for reducing expression of transthyretin mRNA and protein in an animal. Such methods, compounds, and compositions are useful to treat, prevent, delay, or ameliorate transthyretin amyloidosis, or a symptom thereof. |
| 申请公布号 |
EP2563920(A1) |
申请公布日期 |
2013.03.06 |
| 申请号 |
EP20110778071 |
申请日期 |
2011.04.29 |
| 申请人 |
ISIS PHARMACEUTICALS, INC. |
发明人 |
MONIA, BRETT, P.;FREIER, SUSAN, M.;SIWKOWSKI, ANDREW, M. |
| 分类号 |
C12N15/113;A61K31/712;A61P25/28 |
主分类号 |
C12N15/113 |
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