| 发明名称 |
NAPHTHRIDINE DERIVATIVES AS PI3K INHIBITORS FOR THE TREATMENT OF CANCER AND IMMUNE-INFLAMMATORY DISEASES |
| 摘要 |
<p>Compounds of formulae (I) and (II): or a pharmaceutically acceptable salt thereof, wherein: R1 is a nitrogen-containing 5 to 7-membered heteroaryl or heterocycle; R2 and R3 are each independently (LQ)mY, are described. The compounds are PI3K inhibitors and are useful for the treatment of cancer and immune-inflammatory diseases.</p> |
| 申请公布号 |
EP2563788(A1) |
申请公布日期 |
2013.03.06 |
| 申请号 |
EP20110719612 |
申请日期 |
2011.04.26 |
| 申请人 |
KARUS THERAPEUTICS LIMITED |
发明人 |
SHUTTLEWORTH, STEPHEN, JOSEPH;SILVA, FRANCK, ALEXANDRE |
| 分类号 |
C07D471/04;A61K31/4375;A61P29/00;A61P35/00;A61P37/00 |
主分类号 |
C07D471/04 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
