<p>The invention relates to nucleic acid aptamers having the ability to bind human SPARC protein (osteonectin) with specificity. The invention also relates to compositions including such aptamers, as well as methods of identifying such aptamers. The invention further relates to methods for using such aptamers in treating and diagnosing proliferative diseases such as, e.g., cancer.</p>
申请公布号
EP2563397(A2)
申请公布日期
2013.03.06
申请号
EP20110775704
申请日期
2011.05.02
申请人
ABRAXIS BIOSCIENCE, LLC;MOTAMED, KOUROS;DAI, YANSHAN;TRIEU, VUONG;DESAI, NEIL
发明人
MOTAMED, KOUROS;DAI, YANSHAN;TRIEU, VUONG;DESAI, NEIL