发明名称 |
A METHOD, AN INSTALLATION, AND A COMPUTER PROGRAM FOR ESTIMATING THE INITIAL SIZE OF A POPULATION OF NUCLEIC ACIDS, IN PARTICULAR BY PCR |
摘要 |
In order to estimate the size of an initial population of nucleic acids in a sample of interests, in particular by PCR, the following steps are performed: (a) providing a model of the effectiveness of the PCR, the model comprising a constant stage followed by a non-constant stage, the stages being united b a changeover region having a changeover index; (b) using the model of effectiveness to express a relationship between the changeover index and a parameter representative of the initial population size; and (c) determining the changeover index by comparison with the experimental measurements, and deducing therefrom the initial population size in the sample of interest.
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申请公布号 |
CA2589129(C) |
申请公布日期 |
2013.03.05 |
申请号 |
CA20052589129 |
申请日期 |
2005.11.18 |
申请人 |
BIO-RAD PASTEUR;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE |
发明人 |
PIOT, KARINE;MARTINEAU, PIERRE;LAMOURE, CLAIRE;MOLINA, FRANCK |
分类号 |
G06F19/10;C12P19/34;C12Q1/68;G06F19/00;G06F19/24 |
主分类号 |
G06F19/10 |
代理机构 |
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