| 摘要 |
A process is provided for the production of a tissue scaffolding matrix, the matrix comprising a first phase and a second phase contained within the first phase. The process comprises the steps of: bringing the material of the first phase, which is selected from a plastic solid or a solid that is in powder, granule or grain form, into a fluid state, wherein the term fluid defines any substance which flows and wherein in this step the material of the first phase is partially liquefied, or is rendered sufficiently fluid to be able to mix with and carry or coat the material of the second phase, or is rendered soft or tacky such that it is able to coat the material of the second phase, introducing the material of the second phase into the first phase, mixing the first and second phases such that the second phase is contained within and distributed through the first phase, and allowing the first phase to solidify to form a solid or semi-solid state with the second phase contained within and distributed through the first phase to form the matrix, said matrix having a porous structure. In the process of the invention the pore structure is formed by the first and/or second phase comprising particulate material and gaps being present between particles of the or each phase, in addition to any inherent porosity of the particles themselves. |
