发明名称 |
Recombinant microorganism that expresses a secY gene with deletion of sporulation-associated genes and method of producing thereof |
摘要 |
A recombinant microorganism having improved productivity for a protein or a polypeptide, and a method for producing a protein or a polypeptide using the recombinant microorganism, are provided. A recombinant microorganism obtained by transfecting a gene for encoding a desired protein or polypeptide into a microorganism strain which is obtained by genetically constructing to overexpress secY gene of Bacillus subtilis or a gene corresponding to the secY gene, and deleting or inactivating one or more genes selected from sporulation-associated genes and genes corresponding to the sporulation-associated genes from the genome. |
申请公布号 |
US8389264(B2) |
申请公布日期 |
2013.03.05 |
申请号 |
US20080530135 |
申请日期 |
2008.04.08 |
申请人 |
LIU SHENGHAO;ENDO KEIJI;ARA KATSUTOSHI;KAO CORPORATION |
发明人 |
LIU SHENGHAO;ENDO KEIJI;ARA KATSUTOSHI |
分类号 |
C12N1/21 |
主分类号 |
C12N1/21 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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