发明名称 |
SUBSTITUTED 2-ALKYL-1-OXO-N-PHENYL-3-HETEROARYL-1,2,3,4- TETRAHYDROISOQUINOLINE-4-CARBOXAMIDES FOR ANTIMALARIAL THERAPIES |
摘要 |
In one aspect, the invention relates to novel substituted 2-alkyl-1-oxo-N-phenyl-3-heteroaryl-,2,3,4-tetrahydroisoquinoline-4-carboxamides; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating and/or preventing malaria. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
申请公布号 |
CA2846507(A1) |
申请公布日期 |
2013.02.28 |
申请号 |
CA20122846507 |
申请日期 |
2012.08.24 |
申请人 |
ST. JUDE CHILDREN'S RESEARCH HOSPITAL;MMV MEDICINES FOR MALARIA VENTURE;RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY |
发明人 |
GUY, RODNEY KIPLIN;ZHU, FANGYI;GUIGUEMDE, WENDYAM ARMAND;FLOYD, DAVID;KNAPP, SPENCER;STEIN, PHILIP;CASTRO, STEVE |
分类号 |
C07D217/26;A61K31/47;A61P33/06;C07D401/04;C07D405/04;C07D413/04;C07D417/04 |
主分类号 |
C07D217/26 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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