发明名称 |
2 -AMINO-4 - (PYRIDIN- 2 -YL) - 5, 6 -DIHYDRO-4H- 1, 3 -OXAZINE DERIVATIVES AND THEIR USE AS BACE-1 AND/OR BACE - 2 INHIBITORS |
摘要 |
<p>The invention relates to novel oxazine derivatives of formula (I), and pharmaceutically acceptable salts thereof, in which all of the variables are as defined in the specification, pharmaceutical compositions thereof, combinations thereof, and their use as medicaments, particularly for the treatment of Alzheimer's Disease or diabetes via inhibition of BACE-1 or BACE-2.</p> |
申请公布号 |
WO2013027188(A1) |
申请公布日期 |
2013.02.28 |
申请号 |
WO2012IB54269 |
申请日期 |
2012.08.23 |
申请人 |
NOVARTIS AG;LUEOEND, RAINER MARTIN;MACHAUER, RAINER;RUEEGER, HEINRICH;VEENSTRA, SIEM JACOB |
发明人 |
LUEOEND, RAINER MARTIN;MACHAUER, RAINER;RUEEGER, HEINRICH;VEENSTRA, SIEM JACOB |
分类号 |
C07D413/14;A61K31/5355;A61P3/04;A61P3/10;A61P9/12;A61P25/28 |
主分类号 |
C07D413/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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