发明名称 ANTIGEN BINDING PROTEINS TO PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 (PCSK9)
摘要 Antigen binding proteins that interact with Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to PCSK9 are described. Methods of detecting the amount of PCSK9 in a sample using an antigen binding protein to PCSK9 are described.
申请公布号 US2013052201(A1) 申请公布日期 2013.02.28
申请号 US201213656392 申请日期 2012.10.19
申请人 AMGEN, INC.;AMGEN, INC. 发明人 JACKSON SIMON MARK;WALKER NIGEL PELHAM CLINTON;PIPER DEREK EVAN;SHAN BEI;SHEN WAYNE;CHAN JOYCE CHI YEE;KING CHADWICK TERENCE;KETCHEM RANDAL ROBERT;MEHLIN CHRISTOPHER;CARABEO TERESA ARAZAS;CAO QIONG
分类号 A61K39/395;A61P3/06 主分类号 A61K39/395
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