发明名称 |
Self-Assembled Bead-Based Multiplexed Assay For Antigen-Specific Antibodies |
摘要 |
A flexible method for making multiplexed assays for antigen-specific antibody responses is disclosed herein. The method of the present invention comprises incubation of a substrate or a set of beads coated with a dockerin or a cohesin protein with a cohesin or dockerin-antigen fusion proteins to attach the fusion protein essentially irreversibly by non-covalent interaction. The present invention enables the use of one dockerin- or cohesin-coated bead for multiple sets of cohesin- or dockerin-antigens, obviating the need to directly chemically couple new antigens to new beads. |
申请公布号 |
US2013053271(A1) |
申请公布日期 |
2013.02.28 |
申请号 |
US201213594397 |
申请日期 |
2012.08.24 |
申请人 |
ZURAWSKI GERARD;ZURAWSKI SANDRA;BAYLOR RESEARCH INSTITUTE |
发明人 |
ZURAWSKI GERARD;ZURAWSKI SANDRA |
分类号 |
C40B30/04;B01D15/08;B82Y15/00;C07H21/00;C07K1/22;C07K14/00;C07K16/00;C07K19/00;C12N1/00;C12N9/00;C12Q1/70;G01N21/64;G01N21/78;G01N33/566;G01N33/569;G01N33/571;G01N33/573 |
主分类号 |
C40B30/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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