ANTI-MÜLLERIAN HORMONE CHANGES IN PREGNANCY AND PREDICTION OFADVERSE PREGNANCY OUTCOMES AND GENDER
摘要
The present invention provides for methods for evaluating the risk of an adverse pregnancy outcome in a subject and methods for treating subjects evaluated as being high risk. In some aspects, the present invention provides a method of evaluating the risk of an adverse pregnancy outcome in a subject, where if the subject does have an abnormal level of AMH as compared to a predetermined normal level the subject is more likely to have an adverse pregnancy outcome, and if the subject does not have an abnormal level of AMH the subject is less likely to have an adverse pregnancy outcome. In other aspects, the present invention provides a method of determining the gender of a fetus comprising obtaining information regarding the level of AMH in a sample from a pregnant subject.
申请公布号
WO2012158238(A3)
申请公布日期
2013.02.28
申请号
WO2012US26913
申请日期
2012.02.28
申请人
UNIVERSITY OF IOWA RESEARCH FOUNDATION;STEGMANN, BARBARA, J.;SANTILLAN, DONNA, ANN;SANTILLAN, MARK, K.
发明人
STEGMANN, BARBARA, J.;SANTILLAN, DONNA, ANN;SANTILLAN, MARK, K.