| 发明名称 |
SERINE/THREONINE PAK1 INHIBITORS |
| 摘要 |
<p>Compounds having the formula I wherein A, Z, R1a, R1b, R2, R3, R4, R5, R6, R7, R9, R10, Ra, Rb and n are as defined herein are inhibitors of PAK1. Also disclosed are compositions and methods for treating cancer and hyperproliferative disorders.</p> |
| 申请公布号 |
WO2013026914(A1) |
申请公布日期 |
2013.02.28 |
| 申请号 |
WO2012EP66468 |
申请日期 |
2012.08.24 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG;ALIAGAS-MARTIN, IGNACIO;CRAWFORD, JAMES;LEE, WENDY;MATHIEU, SIMON;RUDOLPH, JOACHIM |
发明人 |
ALIAGAS-MARTIN, IGNACIO;CRAWFORD, JAMES;LEE, WENDY;MATHIEU, SIMON;RUDOLPH, JOACHIM |
| 分类号 |
C07D403/14;A61K31/506;A61P35/00 |
主分类号 |
C07D403/14 |
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