发明名称 |
Methods of Inducing Tissue Regeneration |
摘要 |
Methods are provided for producing cells within a lineage (lineage restricted cells) from post-mitotic differentiated cells of the same lineage ex vivo and in vivo, and for treating a subject in need of tissue regeneration therapy by employing these lineage-restricted cells. In addition, the production of lineage restricted cells from postmitotic tissues derived from patients with diseases allows for a characterization of pathways that have gone awry in these diseases and for screening of drugs that will ameliorate or correct the defects as a means of novel drug discovery. Also provided are kits for performing these methods. |
申请公布号 |
US2013052267(A1) |
申请公布日期 |
2013.02.28 |
申请号 |
US201213560709 |
申请日期 |
2012.07.27 |
申请人 |
BLAU HELEN M.;PAJCINI KOSTANDIN;POMERANTZ JASON |
发明人 |
BLAU HELEN M.;PAJCINI KOSTANDIN;POMERANTZ JASON |
分类号 |
A61K35/12;A61K9/00;A61K9/14;A61P1/16;A61P1/18;A61P3/10;A61P9/00;A61P19/00;A61P25/00;A61P25/16;A61P25/28;C09K3/00;C12N5/071;C12N5/077;C12N5/079;C12N5/0793;C12N13/00;C12N15/06;C12N15/113;C12N15/85;C12N15/86;C12N15/861;C12N15/867;C12N15/869;C12N15/88 |
主分类号 |
A61K35/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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