发明名称 REAGENTLESS CERIA-BASED COLORIMETRIC SENSOR
摘要 A colorimetric reagent in the form of nanoparticles, composite nanoparticles, and nanoparticle coatings, including methods of use, methods of preparation, deposition, and assembly of related devices and specific applications. The colorimetric reagent comprises cerium oxide nanoparticles which are used in solution or immobilized on a solid support, either alone or in conjunction with oxidase enzymes, to form an active colorimetric component that reacts with an analyte to form a colored complex. The rate of color change and the intensity of the color are proportional to the amount of analyte present in the sample. Also described is the use of ceria and doped ceria nanoparticles as an oxygen storage/delivery vehicle for oxidase enzymes and applications in biocatalytic processes in anaerobic conditions of interest in biomedicine and bioanalysis. Further described are a variety of related applications of the disclosed technology including clinical diagnosis, in vivo implantable devices, food safety, and fermentation control.
申请公布号 WO2012170851(A3) 申请公布日期 2013.02.28
申请号 WO2012US41608 申请日期 2012.06.08
申请人 CLARKSON UNIVERSITY;ANDREESEU, EMANUELA, SILVANA;ORNATSKA, MARYNA;ISPAS, CRISTINA R.;ANDREESCU, DANIEL 发明人 ANDREESEU, EMANUELA, SILVANA;ORNATSKA, MARYNA;ISPAS, CRISTINA R.;ANDREESCU, DANIEL
分类号 G01N31/22;G01N21/77;G01N21/78 主分类号 G01N31/22
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