发明名称 |
Hetero ring compound |
摘要 |
[Problem] To provide a compound which is useful as a novel and excellent prophylactic and/or therapeutic agent for rejection in various types of organ transplantation, allergic diseases, autoimmune diseases and blood tumors, and which acts in a manner relying on a PI3Kδ-selective inhibitory activity and/or an IL-2-production-inhibiting activity and/or a B-cell-proliferation-inhibiting activity (including an activation-inhibiting activity). [Solution] Examination was made on compounds each having a PI3Kδ-selective inhibitory activity and/or an IL-2-production-inhibiting activity and/or a B-cell-proliferation-inhibiting activity (including an activation-inhibiting activity), and it has been confirmed that a hetero ring compound having a chemical structure represented by formula (I) has a PI3Kδ-selective inhibitory activity and/or an IL-2-production-inhibiting activity and/or a B-cell-proliferation-inhibiting activity (including an activation-inhibiting activity). |
申请公布号 |
AU2011290189(A1) |
申请公布日期 |
2013.02.28 |
申请号 |
AU20110290189 |
申请日期 |
2011.08.09 |
申请人 |
ASTELLAS PHARMA INC. |
发明人 |
SHIWAKU, MASAHIKO;TAKAHASHI, FUMIE;IMADA, SUNAO;ASANO, TORU;KOZUKI, YOSHIHIRO;MAEDA, JUNKO;KATO, KOJI;FUKAHORI, HIDEHIKO |
分类号 |
C07D401/14;A61K31/5377;A61K31/541;A61K31/55;A61P1/04;A61P11/06;A61P17/06;A61P19/02;A61P29/00;A61P35/02;A61P37/02;A61P37/06;A61P37/08;A61P43/00;C07D403/04;C07D403/14;C07D405/14;C07D409/14;C07D413/14;C07D417/14;C07D471/04;C07D471/10 |
主分类号 |
C07D401/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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