NONTOXIC, WATER-SOLUBLE AND FUNCTIONALIZED TRANSITION METAL ION DOPED SEMICONDUCTOR NANOCRYSTALS AND A PROCESS FOR THE PREPARATION THEREOF

摘要

The present invention deals with nontoxic, water soluble and functionalized transition metal ion doped ZnS semiconductor nanocrystals. These nanocrystals are effective in fluorescent biological labeling and can be used as bioconjugates useful for different biomedical applications. The present invention further includes within its scope a process for preparing these functionalized transition metal ion doped semiconductor nanocrystals comprising the steps of polymer coating, polymerization followed by purification and functionalization, providing long shelf life. The present invention also includes a process of fluorescence biological labeling with the nontoxic, water soluble and functionalized transition metal ion doped semiconductor nanocrystals for long term cell imaging applications.