摘要 |
<p>The present invention relates to a process for preparing a compound of formula (IV) where W is the methyl ( E )-2-(3-methoxy)acrylate group, which comprises the steps of: (i) reacting the compound of formula (IV) where W is the methyl 2-(3,3-dimethoxy)propanoate group with a reagent that will protect the hydroxyl group of that compound from reaction during subsequent demethanolysis; (ii) eliminating methanol from the hydroxyl-protected compound formed in step (i); and (iii) removing the hydroxyl-protecting group formed in step (i) to form a compound of formula (IV) where W is the methyl ( E )-2-(3-methoxy)acrylate group.</p> |