发明名称 |
FUSED HETEROCYCLIC DERIVATIVES AS S1P MODULATORS |
摘要 |
<p>The present invention relates to a fused heterocyclic derivative of the formula (I) The variables R1-R4, z, A, Q, X and Y are as defined in the claims. The following heterocycles are exemplified substructures of formula (I): The compounds of formula (I) are modulators of the S1P receptor (Sphingosine-1-phosphate receptor), More specifically, they are agonists of S1P5. The compounds have therapeutic use in treatment of cognitive disorders, age-relate cognitive decline and dementia.</p> |
申请公布号 |
SG186952(A1) |
申请公布日期 |
2013.02.28 |
申请号 |
SG20130000997 |
申请日期 |
2011.07.08 |
申请人 |
ABBVIE B.V. |
发明人 |
SMID, PIETER;IWEMA BAKKER, WOUTER, I.;COOLEN, HEIN, K.A.C.;SLIEDREGT, LEONARDUS, A.J.M.;VAN DONGEN, MARIA, J.P.;DEN HARTOG, JACOBUS, A.J. |
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