| 发明名称 |
ORGANIC COMPOSITIONS TO TREAT BETA-ENaC-RELATED DISEASES |
| 摘要 |
The present disclosure relates to RNAi agents useful in methods of treating Beta-ENaC-related diseases such as cystic fibrosis, pseudohypoaldosteronism type 1 (PHA1), Liddle's syndrome, hypertension, alkalosis, hypokalemia, and obesity-associated hypertension, using a therapeutically effective amount of a RNAi agent to Beta-ENaC. |
| 申请公布号 |
EP2561077(A1) |
申请公布日期 |
2013.02.27 |
| 申请号 |
EP20110715243 |
申请日期 |
2011.04.20 |
| 申请人 |
NOVARTIS AG |
发明人 |
DE FOUGEROLLES, ANTONIN;DIENER, JOHN, L.;HICKMAN, EMMA;HINKLE, GREGORY;MILSTEIN, STUART;PULICHINO, ANNE-MARIE;SPRAGUE, ANDREW |
| 分类号 |
C12N15/113;A61K31/713;A61P3/12 |
主分类号 |
C12N15/113 |
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