发明名称 METHOD OF DETERMINING DEGREE OF IMPAIRMENT OF BLOOD AGGREGATE STATE
摘要 FIELD: medicine.SUBSTANCE: invention relates to medicine, namely to clinical diagnostics, and can be used as express-method of detecting impairment of blood aggregate state. For this purpose echcardiographic and electrocardiographic examinations are performed, systolic arterial pressure and body temperature are measured. Obtained data are processed and obtained characteristic is used to carry out comparison with control characteristic, preliminarily obtained after processing of data of echcardiographic and electrocardiographic examinations, measurement of systolic pressure, temperature in healthy blood donors. Results of comparison are used to judge about degree of impairment of blood aggregate state, as control characteristic used is digital characteristic of degree of hemoaggregation interaction in blood flow (HAWR), which is calculated by formulawhere Wng is potential energy of blood gravitation field Wng = -? M; Wne is potential energy of blood electric field Wne = LMTY; Wnc is potential energy of coagulation chemical interaction Wnc = ? (ni×Eci); Wk is kinetic energy of blood flow Wk = MV/2, M is weight of circulating blood volume; G is gravitational potential of earth, L is length of arterial section of blood flow; Y is current intensity in volume conductor; ni is number of bonds of molecules of blood cells; Eci is average value of bond energies; V is rate of blood flow in output part of left ventricle; P is systolic arterial pressure; T is absolute temperature. If HAWR>9.82, degree of impairment of aggregation potential is determined as hypercoagulation. If HAWR<9.64, impairment is determined as hypocoagulation. If HAWR is 9.64-9.82, it is determined as normal aggregate blood state.EFFECT: method makes it possible to determine degree of impairment of blood aggregate state in efficient non-invasive way.1 tbl, 4 ex
申请公布号 RU2476146(C1) 申请公布日期 2013.02.27
申请号 RU20110136151 申请日期 2011.08.31
申请人 FEDERAL'NOE GOSUDARSTVENNOE BJUDZHETNOE UCHREZHDENIE "NAUCHNYJ TSENTR SERDECHNO-SOSUDISTOJ KHIRURGII IMENI A.N. BAKULEVA" ROSSIJSKOJ AKADEMII MEDITSINSKIKH NAUK (FGBU "NTSSSKH IM.A.N.BAKULEVA" RAMN) 发明人 BOKERIJA LEONID ANTONOVICH;GAVRILOV OLEG KONSTANTINOVICH;SOKOL'SKAJA NADEZHDA OLEGOVNA;SOKOL'SKAJA MARIJA ALEKSANDROVNA
分类号 A61B5/0402;A61B5/01;A61B5/02;A61B8/06 主分类号 A61B5/0402
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