发明名称 WATER-SOLUBLE PHARMACEUTICAL COMPOSITION COMPRISING AT LEAST ONE THERAPEUTICALLY ACTIVE SUBSTANCE HAVING HYDROPHOBIC PROPERTIES AND AT LEAST ONE COMPOUND SELECTED FROM AMONG SIALOGLYCOSPHINGOLIPIDS, GLYCOSPHINGOLIPIDS OR A MIXTURE OF SIALOGLYCOSPHINGOLIPIDS AND GLYCOSPHINGOLIPIDS
摘要 This invention discloses water soluble pharmaceutical compositions including at least one therapeutically active substance and at least one compound selected from the sialoglycosphingolipids, the glycosphingolipids or a mixture of sialoglicosphingolipids and glycosphingolipids, in which at least one of the therapeutically active substances is a drug with hydrophobic characteristics. In particular, sterile compositions for i.v. administration, composed of nano-glycosphingolipids micelles or modified glycosphingolipids, which can be coated with albumin in a noncovalent form and which allow transport and controlled release of highly hydrophobic molecules are disclosed.
申请公布号 EP2561861(A1) 申请公布日期 2013.02.27
申请号 EP20110755731 申请日期 2011.03.14
申请人 CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS YTECNICAS (CONICET);CENTRO DE EXCELENCIA EN PRODUCTOS Y PROCESOS DE CORDOBA (CEPROCOR) 发明人 LEONHARD, VICTORIA;ALASINO, VALERIA;BIANCO, ISMAEL;BELTRAMO, DANTE
分类号 A61K9/107;A61K31/337;A61K31/704;A61K31/7048;A61P31/10;A61P35/00 主分类号 A61K9/107
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