发明名称 |
WATER-SOLUBLE PHARMACEUTICAL COMPOSITION COMPRISING AT LEAST ONE THERAPEUTICALLY ACTIVE SUBSTANCE HAVING HYDROPHOBIC PROPERTIES AND AT LEAST ONE COMPOUND SELECTED FROM AMONG SIALOGLYCOSPHINGOLIPIDS, GLYCOSPHINGOLIPIDS OR A MIXTURE OF SIALOGLYCOSPHINGOLIPIDS AND GLYCOSPHINGOLIPIDS |
摘要 |
This invention discloses water soluble pharmaceutical compositions including at least one therapeutically active substance and at least one compound selected from the sialoglycosphingolipids, the glycosphingolipids or a mixture of sialoglicosphingolipids and glycosphingolipids, in which at least one of the therapeutically active substances is a drug with hydrophobic characteristics. In particular, sterile compositions for i.v. administration, composed of nano-glycosphingolipids micelles or modified glycosphingolipids, which can be coated with albumin in a noncovalent form and which allow transport and controlled release of highly hydrophobic molecules are disclosed. |
申请公布号 |
EP2561861(A1) |
申请公布日期 |
2013.02.27 |
申请号 |
EP20110755731 |
申请日期 |
2011.03.14 |
申请人 |
CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS YTECNICAS (CONICET);CENTRO DE EXCELENCIA EN PRODUCTOS Y PROCESOS DE CORDOBA (CEPROCOR) |
发明人 |
LEONHARD, VICTORIA;ALASINO, VALERIA;BIANCO, ISMAEL;BELTRAMO, DANTE |
分类号 |
A61K9/107;A61K31/337;A61K31/704;A61K31/7048;A61P31/10;A61P35/00 |
主分类号 |
A61K9/107 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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