| 发明名称 |
Modulation of BCL11A for treatment of hemoglobinopathies |
| 摘要 |
The invention relates to methods and uses of modulating fetal hemoglobin expression (HbF) in a hematopoietic progenitor cells via inhibitors of BCL11A expression or activity, such as RNAi and antibodies.
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| 申请公布号 |
US8383604(B2) |
申请公布日期 |
2013.02.26 |
| 申请号 |
US200913063524 |
申请日期 |
2009.09.14 |
| 申请人 |
CHILDREN'S MEDICAL CENTER CORPORATION;PRESIDENT AND FELLOWS OF HARVARD COLLEGE;ORKIN STUART H.;SANKARAN VIJAY G. |
发明人 |
ORKIN STUART H.;SANKARAN VIJAY G. |
| 分类号 |
C07H21/02;C07K14/00;C12N5/071;C12N15/113 |
主分类号 |
C07H21/02 |
| 代理机构 |
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| 地址 |
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