发明名称 |
G proteins in tumor growth and angiogenesis |
摘要 |
The invention provides an agent that reduces the expression of Gα12 or Gα13 polypeptide, as well as an agent that enhances G protein Gα12 or Gα13 expression and/or activity. An agent of the invention may be used to decrease or increase G protein Gα12 or Gα13 expression and/or activity thereby to treat or prevent the onset of a disease or condition associated with Gα12 or Gα13 expression and/or activity. The invention also provides a method for screening for an anti-cancer or anti-angiogenesis agent, as well as an agent that promotes angiogenesis.
|
申请公布号 |
US8383597(B2) |
申请公布日期 |
2013.02.26 |
申请号 |
US20070805715 |
申请日期 |
2007.05.24 |
申请人 |
CORNELL RESEARCH FOUNDATION, INC.;HUANG XIN-YUN |
发明人 |
HUANG XIN-YUN |
分类号 |
A61K31/70;C07H21/02;C07H21/04 |
主分类号 |
A61K31/70 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|