发明名称 |
SINGLE RECOMBINATION SYSTEM AND METHODS OF USE |
摘要 |
Disclosed is a modified poxvirus vector that allows for the generation of recombinant poxviruses by a single recombination event. A modified poxvirus vector comprising at least one reporter gene located between two flanking sequences for homologous recombination and a selection gene whose expression is regulated by the tetracycline operator/repressor system. Furthermore, a host cell comprising said vector and a method for the generation of recombinant poxviruses using said vector are provided.
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申请公布号 |
NZ593385(A) |
申请公布日期 |
2013.02.22 |
申请号 |
NZ20090593385 |
申请日期 |
2009.12.16 |
申请人 |
EMERGENT PRODUCT DEVELOPMENT GERMANY GMBH |
发明人 |
LEYRER, SONJA;MAYER, KATJA |
分类号 |
C12N15/863;A61K39/00 |
主分类号 |
C12N15/863 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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