| 发明名称 |
SUMO AS A MARKER OF CANCER DEVELOPMENT AND TARGET FOR CANCER THERAPY |
| 摘要 |
Disclosed herein are methods relating to inhibiting or reducing proliferation of a cancer cell, for treating cancer in a subject in need of treatment, predicting the risk of progression of cancer to a more aggressive cancer, and screening for cancer in a subject, that comprise detecting and/or decreasing the levels of SUMO conjugated proteins and detecting and/or interfering with SUMO conjugation.
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| 申请公布号 |
US2013046010(A1) |
申请公布日期 |
2013.02.21 |
| 申请号 |
US201113641639 |
申请日期 |
2011.04.15 |
| 申请人 |
DUKE UNIVERSITY;PASCHEN WULF;YANG WEI;SHENG HUAXIN;WARNER DAVID S. |
发明人 |
PASCHEN WULF;YANG WEI;SHENG HUAXIN;WARNER DAVID S. |
| 分类号 |
A61K31/713;A61K31/7105;A61P35/00;C12N5/09;C12Q1/68;C40B30/04;G01N33/574 |
主分类号 |
A61K31/713 |
| 代理机构 |
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代理人 |
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| 主权项 |
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