| 摘要 |
The present invention provides a microvesicle membrane protein CSE1L and application thereof. Disclosed are method and kit comprising CSE1L-binding agent or phosphorylated CSE1L- binding agent for microvesicle isolation or analysis. Also disclosed are CSE1L-binding agents or phosphorylated CSE1L-binding agents, such as anti-CSE1L antibody or anti-phosphorylated CSE1L antibody and derivatives as well as pharmaceutical compositions and kits comprised the antibodies or derivative for detecting CSE1L or phosphorylated CSE1L in microvesicles or fluids from biological samples for disease diagnosis. Also disclosed are method and kit comprising CSE1L-binding agent or phosphorylated CSE1L-binding agent for medical imaging or diseases treatment. |
