MICROORGANISMS FOR PRODUCING N-PROPANOL 1, 3-PROPANEDIOL, 1,2-PROPANEDIOL OR GLYCEROL AND METHODS RELATED THERETO

摘要

Provided herein is a non-naturally occurring microbial organism having a reductive TCA or Wood-Ljungdahl pathway and comprising at least one exogenous nucleic acid encoding said pathway enzymes expressed in a sufficient amount to enhance carbon flux through acetyl-CoA. Also provided herein is a method for enhancing the availability of reducing equivalents in the presence of carbon monoxide or hydrogen, and can include culturing this organism for a sufficient period of time to produce a product.