| 发明名称 |
TGF-beta SIGNAL TRANSDUCTION INHIBITOR |
| 摘要 |
The present invention provides a compound represented by the following formula (I) or a physiologically acceptable salt thereof, and use thereof for the prophylaxis or treatment of TGF-&bgr;-related diseases: wherein Y is a hydrogen atom and the like; R2 is and the like; R3 is —NR8—R9— and the like; R4, R5, R6 and R7 are the same or different and each is a hydrogen atom and the like; and X is and the like.
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| 申请公布号 |
US2013045977(A1) |
申请公布日期 |
2013.02.21 |
| 申请号 |
US201113579843 |
申请日期 |
2011.02.17 |
| 申请人 |
KYOTO UNIVERSITY;KAKEYA HIDEAKI;HATTORI AKIRA;TAKASU YASUAKI;FUJII NOBUTAKA;OISHI SHINYA;KOJIMA SOICHI;HARA MITSUKO |
发明人 |
KAKEYA HIDEAKI;HATTORI AKIRA;TAKASU YASUAKI;FUJII NOBUTAKA;OISHI SHINYA;KOJIMA SOICHI;HARA MITSUKO |
| 分类号 |
A61K31/445;A61K31/4545;A61K31/5377;A61P25/00;A61P35/00;C07D211/32;C07D401/12;C07D413/12 |
主分类号 |
A61K31/445 |
| 代理机构 |
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