发明名称 |
Methods for forming dyed microspheres and populations of dyed microspheres |
摘要 |
Various methods for forming dyed microspheres are provided. One method includes activating a chemical structure coupled to a dye using heat or light to form a reaction intermediate in the presence of a microsphere. The reaction intermediate covalently attaches to a polymer of the microsphere thereby coupling the dye to the polymer and forming the dyed microsphere. Additional methods are provided for forming a dyed microsphere coupled to a molecule. These methods include dyeing the microspheres as described above in addition to synthesizing the molecule on an outer surface of the dyed microspheres. A population of dyed microspheres is also provided. Each of the dyed microspheres of the population includes a dye attached to a polymer of each of the dyed microspheres by a chemical structure. A coefficient of variation in dye characteristics of the population of dyed microspheres attributable to the dye is less than about 10%. |
申请公布号 |
EP2559738(A1) |
申请公布日期 |
2013.02.20 |
申请号 |
EP20120184453 |
申请日期 |
2005.10.11 |
申请人 |
LUMINEX CORPORATION |
发明人 |
HOFFACKER, KURT;LUGADE, ANADA, G.;TERPETSCHNIG, EWALD |
分类号 |
C09B69/10;G01N33/58;G01N33/68 |
主分类号 |
C09B69/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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