发明名称 |
METHOD FOR INTRODUCING FOREIGN GENE INTO EARLY EMBRYO OF PRIMATE ANIMAL, AND METHOD FOR PRODUCTION OF TRANSGENIC PRIMATE ANIMAL COMPRISING THE INTRODUCTION METHOD |
摘要 |
<p>An object of the present invention is to provide a method for introducing a gene into an embryo for production of a human disease model primate animal using a non-human primate animal such as a marmoset. The present invention relates to a method for introducing a foreign gene into an early embryo of a non-human primate animal, which comprises placing early embryos of a non-human primate in a 0.2 M to 0.3 M sucrose solution, so as to increase the volume of the perivitelline spaces, and then injecting a viral vector containing a human foreign gene operably linked to a promoter into the perivitelline spaces of the early embryos.</p> |
申请公布号 |
EP2246423(A4) |
申请公布日期 |
2013.02.20 |
申请号 |
EP20080871871 |
申请日期 |
2008.12.09 |
申请人 |
CENTRAL INSTITUTE FOR EXPERIMENTAL ANIMALS;KEIO UNIVERSITY |
发明人 |
SASAKI, ERIKA;OKANO, HIDEYUKI |
分类号 |
C12N15/09;A01K67/027 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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