发明名称 |
TRICYCLIC PYRIDYL-VINYL-PYROLES AS PAR1 INHIBITORS |
摘要 |
This disclosure relates to compounds of formula I: wherein R1, R2, R3, R4, X and Y have the meanings denoted in the disclosure. The compounds of formula I have antithrombotic activity and in particular inhibit the protease-activated receptor 1 (PAR1). The disclosure further relates to a method for producing the compound of formula I and to the use thereof as a pharmaceutical product. |
申请公布号 |
EP2558465(A1) |
申请公布日期 |
2013.02.20 |
申请号 |
EP20110715496 |
申请日期 |
2011.04.14 |
申请人 |
SANOFI |
发明人 |
SCHOENAFINGER, KARL;STEINHAGEN, HENNING;SCHEIPER, BODO;HEINELT, UWE;WEHNER, VOLKMAR;HERRMANN, MATTHIAS |
分类号 |
C07D471/14;A61K31/407;A61K31/437;A61K31/4985;A61K31/5383;A61P7/02;C07D487/14;C07D498/14 |
主分类号 |
C07D471/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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