发明名称 |
TOPICAL TREATMENTS FOR PAIN |
摘要 |
<p>The present invention relates to novel compositions and therapeutic methods for the treatment of pain, in particular neuropathic, ischemic, muscle, arthritic or multiple sclerosis pain. The compositions include a combination of an alpha2-adrenergic agonist or a nitric oxide donor combined with a phosphodiesterase (PDE) or a phosphatidic acid (PA) inhibitor, which have been found to act together synergistically to provide effective treatment for pain, especially when administered topically.</p> |
申请公布号 |
EP2558101(A1) |
申请公布日期 |
2013.02.20 |
申请号 |
EP20110768326 |
申请日期 |
2011.04.13 |
申请人 |
THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING / MCGILL UNIVERSITY |
发明人 |
CODERRE, TERENCE;LAFERRIERE, ANDRE;JEGADEESAN, VAIGUNDA RAGAVENDRAN |
分类号 |
A61K31/5377;A61K31/4168;A61K31/522;A61K45/06;A61P29/00 |
主分类号 |
A61K31/5377 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|