发明名称 AMIDO COMPOUNDS AS RORyt MODULATORS AND USES THEREOF
摘要 Amido compounds are disclosed that have a formula represented by the following: and wherein n1, n2, R 1a , R 1b , R 2 , R 3 , R 4 , R 5 , and R 6 are as described herein. The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, inflammatory conditions, autoimmune disorders, cancer, and graft-versus-host disease.
申请公布号 EP2558087(A1) 申请公布日期 2013.02.20
申请号 EP20110753726 申请日期 2011.03.11
申请人 NEW YORK UNIVERSITY;THE GOVERNMENT OF THE UNITED STATES OF AMERICA ASREPRESENTED BY THE SECRETARY OF THE DEPARTMENT OFHEALTH AND HUMAN SERVICES 发明人 LITTMAN, DAN;HUH, JUN, R.;HUANG, RUILI;HUANG, WENWEI;ENGLUND, ERIKA, ELAINE
分类号 A61K31/535;A61K31/4025;A61K31/404;A61K31/4453;A61K31/4525;A61K31/453;A61K31/495;A61K31/496;A61K31/5375;A61P29/00;A61P37/00;C07C235/34;C07C235/36;C07D211/16;C07D307/52;C07D317/54;C07D317/60;C07D403/14;C07D405/06 主分类号 A61K31/535
代理机构 代理人
主权项
地址