发明名称 |
AMIDO COMPOUNDS AS RORyt MODULATORS AND USES THEREOF |
摘要 |
Amido compounds are disclosed that have a formula represented by the following:
and wherein n1, n2, R 1a , R 1b , R 2 , R 3 , R 4 , R 5 , and R 6 are as described herein. The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, inflammatory conditions, autoimmune disorders, cancer, and graft-versus-host disease. |
申请公布号 |
EP2558087(A1) |
申请公布日期 |
2013.02.20 |
申请号 |
EP20110753726 |
申请日期 |
2011.03.11 |
申请人 |
NEW YORK UNIVERSITY;THE GOVERNMENT OF THE UNITED STATES OF AMERICA ASREPRESENTED BY THE SECRETARY OF THE DEPARTMENT OFHEALTH AND HUMAN SERVICES |
发明人 |
LITTMAN, DAN;HUH, JUN, R.;HUANG, RUILI;HUANG, WENWEI;ENGLUND, ERIKA, ELAINE |
分类号 |
A61K31/535;A61K31/4025;A61K31/404;A61K31/4453;A61K31/4525;A61K31/453;A61K31/495;A61K31/496;A61K31/5375;A61P29/00;A61P37/00;C07C235/34;C07C235/36;C07D211/16;C07D307/52;C07D317/54;C07D317/60;C07D403/14;C07D405/06 |
主分类号 |
A61K31/535 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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