发明名称 |
Method of predicting the clinical response to cisplatin or carboplatin chemotherapeutic treatment |
摘要 |
Method for predicting the survival of a patient suffering from NSCLC to a cisplatin or carboplatin based chemotherapy treatment which comprises the step of determining the methylation state of a nucleic acid encoding 14-3-3 sigma in a biological sample from the patient, wherein the presence of methylation is indicative of longer survival of said patient as a response to said chemotherapy treatment. The methylation status of the 14-3-3 sigma gene can be easily determined in a serum sample.
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申请公布号 |
US8377888(B2) |
申请公布日期 |
2013.02.19 |
申请号 |
US20060908796 |
申请日期 |
2006.03.16 |
申请人 |
PANGAEA BIOTECH, S.A.;COSTA RAFAEL ROSELL;ROCA MIGUEL TARON |
发明人 |
COSTA RAFAEL ROSELL;ROCA MIGUEL TARON |
分类号 |
A61P35/00;C12Q1/68 |
主分类号 |
A61P35/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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