| 发明名称 |
PYRIMIDINES AS PLK INHIBITORS |
| 摘要 |
The present invention encompasses compounds of general formula (1), (see formula 1) wherein A, W, X, Y, Z, Ra, Rb, Rc, R1 and R3 are as defined herein, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, and the use thereof for preparing a pharmaceutical composition having the above-mentioned properties.
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| 申请公布号 |
CA2573371(C) |
申请公布日期 |
2013.02.19 |
| 申请号 |
CA20052573371 |
申请日期 |
2005.08.18 |
| 申请人 |
BOEHRINGER INGELHEIM INTERNATIONAL GMBH |
发明人 |
STADTMUELLER, HEINZ;ENGELHARDT, HARALD;STEEGMAIER, MARTIN;BAUM, ANKE;GUERTLER, ULRICH;SCHOOP, ANDREAS;QUANT, JENS JUERGEN;SOLCA, FLAVIO;HAUPTMANN, RUDOLF;REISER, ULRICH;ZAHN, STEPHAN KARL;HERFURTH, LARS |
| 分类号 |
C07D403/12;A61K31/505;A61K31/506;A61K31/5513;A61K31/553;A61P29/00;A61P35/00;A61P37/00;C07D239/48;C07D401/12;C07D403/14;C07D405/12;C07D413/12 |
主分类号 |
C07D403/12 |
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