发明名称 |
Process for preparing thermosensitive (poly(ethylene oxide) poly(propylene oxide)) derivatives that can be used to functionalize chitosan |
摘要 |
The invention relates to a thermosensitive (poly(ethylene oxide) poly(propylene oxide))-acetal derivative, which can be used to functionalize chitosan, and to the process for the preparation thereof. The invention therefore also relates to a process for functionalizing chitosan by grafting this thermosensitive copolymer and optionally another thermosensitive polymer, poly(ethylene oxide). A subject of the invention is also a chitosan-(poly(ethylene oxide) poly(propylene oxide))-poly(ethylene oxide) derivative which has the advantage of being water-soluble at physiological pH. The invention therefore also relates to the aqueous compositions comprising this derivative and to the use of this composition for the manufacture of gel by heating.
|
申请公布号 |
US8377418(B2) |
申请公布日期 |
2013.02.19 |
申请号 |
US20080677211 |
申请日期 |
2008.09.11 |
申请人 |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS);UNIVERSITE JOSEPH FOURIER-GRENOBLE 1;AUZELY-VELTY RACHEL;CREUZET CAROLINE |
发明人 |
AUZELY-VELTY RACHEL;CREUZET CAROLINE |
分类号 |
A61K51/00;A61K9/22;A61K36/14;C08B37/08 |
主分类号 |
A61K51/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|