CDR REGIONS OF MONOCLONAL ANTIBODY THAT ANTAGONIZE SPHINOGOSINE 1-PHOSPHATE AND RELATED METHODS
摘要
<p>Materials and method for treating cancer and screening for anti-neoplastic agents are provided. These materials and methods can include sphingosine 1 -phosphate antagonists that bind to sphingosine- 1 phosphate receptor subtype 3. Antibodies and aptamers that selectively bind to an epitope in the extracellular loop between transmembrane domains two and three of sphingosine- 1 -phosphate receptor subtype 3 are provided.</p>
申请公布号
WO2013022863(A1)
申请公布日期
2013.02.14
申请号
WO2012US49805
申请日期
2012.08.06
申请人
EXPRESSION DRUG DESIGNS, LLC;HERR, DERON, R.;HARRIS, GREG, L.