发明名称 CYCLOPROPANEAMINE COMPOUND
摘要 The present invention provides a compound which has an inhibitory activity on lysine-specific demethylase 1 and is useful as a medicinal agent such as a prophylactic or therapeutic agent for cancer and central nervous system diseases. The present invention relates to a compound represented by formula (I) [wherein A represents a hydrocarbon or heterocyclic ring group which may have a substituent; R represents H or a hydrocarbon or heterocyclic ring group which may have a substituent; A and R may be bound together to form a ring which may have a substituent; Q1, Q2, Q3 and Q4 independently represent a hydrogen atom or a substituent; Q1 and Q2 or Q3 and Q4 may be bound together to form a ring which may have a substituent; X represents H or a linear hydrocarbon or saturated cyclic group which may have a substituent; Y1, Y2 and Y3 independently represent H or a hydrocarbon or heterocyclic ring group which may have a substituent; X and Y1 or Y1 and Y2 may be bound together to form a ring which may have a substituent; and Z1, Z2 and Z3 independently represent H or a substituent] or a salt thereof.
申请公布号 CA2844525(A1) 申请公布日期 2013.02.14
申请号 CA20122844525 申请日期 2012.08.08
申请人 TAKEDA PHARMACEUTICAL COMPANY LIMITED 发明人 TOMITA, NAOKI;KAJII, SHIGEO;CARY, DOUGLAS ROBERT;TOMITA, DAISUKE;IMAMURA, SHINICHI;TSUCHIDA, KEN;MATSUDA, SATORU;HARA, RYUJIRO
分类号 C07C233/80;A61K31/167;A61K31/36;A61K31/366;A61K31/381;A61K31/40;A61K31/402;A61K31/4035;A61K31/404;A61K31/4184;A61K31/42;A61K31/421;A61K31/426;A61K31/428;A61K31/429;A61K31/433;A61K31/4406;A61K31/4409;A61K31/4453;A61K31/4468;A61K31/451;A61K31/495;A61K31/55;A61P35/00;A61P35/02;C07C235/56;C07C237/40;C07C271/22;C07D207/06;C07D207/337;C07D209/08;C07D209/42;C07D209/46;C07D209/48;C07D211/56;C07D211/58;C07D211/76;C07D213/04;C07D213/38;C07D213/56;C07D223/16;C07D231/14;C07D231/20;C07D231/22;C07D231/56;C07D233/61;C07D233/64;C07D239/36;C07D261/08;C07D261/10;C07D263/32;C07D263/34;C07D277/20;C07D277/28;C07D277/30;C07D277/62;C07D285/06;C07D295/14;C07D309/14;C07D317/58;C07D333/20;C07D405/04;C07D409/04;C07D471/04;C07D495/04;C07D513/04 主分类号 C07C233/80
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